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BMCBI
2008
136views more  BMCBI 2008»
15 years 6 months ago
LOMA: A fast method to generate efficient tagged-random primers despite amplification bias of random PCR on pathogens
Background: Pathogen detection using DNA microarrays has the potential to become a fast and comprehensive diagnostics tool. However, since pathogen detection chips currently utili...
Wah-Heng Lee, Christopher W. Wong, Wan Yee Leong, ...
BMCBI
2008
138views more  BMCBI 2008»
15 years 6 months ago
Combining transcriptional datasets using the generalized singular value decomposition
Background: Both microarrays and quantitative real-time PCR are convenient tools for studying the transcriptional levels of genes. The former is preferable for large scale studies...
Andreas W. Schreiber, Neil J. Shirley, Rachel A. B...
BMCBI
2008
150views more  BMCBI 2008»
15 years 6 months ago
BibGlimpse: The case for a light-weight reprint manager in distributed literature research
Background: While text-mining and distributed annotation systems both aim at capturing knowledge and presenting it in a standardized form, there have been few attempts to investig...
Thomas Tüchler, Golda Velez, Alexandra Graf, ...
BMCBI
2008
242views more  BMCBI 2008»
15 years 6 months ago
annot8r: GO, EC and KEGG annotation of EST datasets
Background: The expressed sequence tag (EST) methodology is an attractive option for the generation of sequence data for species for which no completely sequenced genome is availa...
Ralf Schmid, Mark L. Blaxter
BMCBI
2008
107views more  BMCBI 2008»
15 years 6 months ago
Multi-agent systems in epidemiology: a first step for computational biology in the study of vector-borne disease transmission
Background: Computational biology is often associated with genetic or genomic studies only. However, thanks to the increase of computational resources, computational models are ap...
Benjamin Roche, Jean-François Guégan...