Background: A major obstacle in treatment of HIV is the ability of the virus to mutate rapidly into drug-resistant variants. A method for predicting the susceptibility of mutated ...
Maris Lapinsh, Martin Eklund, Ola Spjuth, Peteris ...
Background: Event sequences where different types of events often occur close together arise, e.g., when studying potential transcription factor binding sites (TFBS, events) of ce...
Background: DNA microarrays are used to investigate differences in gene expression between two or more classes of samples. Most currently used approaches compare mean expression l...
Background: Both microarrays and quantitative real-time PCR are convenient tools for studying the transcriptional levels of genes. The former is preferable for large scale studies...
Andreas W. Schreiber, Neil J. Shirley, Rachel A. B...
Background: Mixture models of mutagenetic trees are evolutionary models that capture several pathways of ordered accumulation of genetic events observed in different subsets of pa...