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BMCBI
2005
190views more  BMCBI 2005»
15 years 6 months ago
An Entropy-based gene selection method for cancer classification using microarray data
Background: Accurate diagnosis of cancer subtypes remains a challenging problem. Building classifiers based on gene expression data is a promising approach; yet the selection of n...
Xiaoxing Liu, Arun Krishnan, Adrian Mondry
BMCBI
2005
107views more  BMCBI 2005»
15 years 6 months ago
An edit script for taxonomic classifications
Abstract. Taxonomy provides one of the most powerful ways to navigate sequence data bases but currently, users are forced to formulate queries according to a single taxonomic class...
Roderic D. M. Page, Gabriel Valiente
BMCBI
2005
106views more  BMCBI 2005»
15 years 6 months ago
SIMPROT: Using an empirically determined indel distribution in simulations of protein evolution
Background: General protein evolution models help determine the baseline expectations for the evolution of sequences, and they have been extensively useful in sequence analysis an...
Andy Pang, Andrew D. Smith, Paulo A. S. Nuin, Elis...
BMCBI
2005
97views more  BMCBI 2005»
15 years 6 months ago
Evolutionary distance estimation and fidelity of pair wise sequence alignment
Background: Evolutionary distances are a critical measure in comparative genomics and molecular evolutionary biology. A simulation study was used to examine the effect of alignmen...
Michael S. Rosenberg
BMCBI
2005
97views more  BMCBI 2005»
15 years 6 months ago
Phylogenetic reconstruction of ancestral character states for gene expression and mRNA splicing data
Background: As genomes evolve after speciation, gene content, coding sequence, gene expression, and splicing all diverge with time from ancestors with close relatives. A minimum e...
Roald Rossnes, Ingvar Eidhammer, David A. Liberles
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