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BIOINFORMATICS
2006
120views more  BIOINFORMATICS 2006»
15 years 6 months ago
Comparison of Affymetrix GeneChip expression measures
Motivation: In the Affymetrix GeneChip system, preprocessing occurs before one obtains expression level measurements. Because the number of competing preprocessing methods was lar...
Rafael A. Irizarry, Zhijin Wu, Harris A. Jaffee
BMCBI
2006
120views more  BMCBI 2006»
15 years 6 months ago
A factor analysis model for functional genomics
Background: Expression array data are used to predict biological functions of uncharacterized genes by comparing their expression profiles to those of characterized genes. While b...
Rafal Kustra, Romy Shioda, Mu Zhu
BMCBI
2006
105views more  BMCBI 2006»
15 years 6 months ago
Integrative investigation of metabolic and transcriptomic data
Background: New analysis methods are being developed to integrate data from transcriptome, proteome, interactome, metabolome, and other investigative approaches. At the same time,...
Pinar Pir, Betül Kirdar, Andrew Hayes, Z. Ils...
BMCBI
2006
98views more  BMCBI 2006»
15 years 6 months ago
The Secrets of a Functional Synapse - From a Computational and Experimental Viewpoint
Background: Neuronal communication is tightly regulated in time and in space. The neuronal transmission takes place in the nerve terminal, at a specialized structure called the sy...
Michal Linial
BMCBI
2006
87views more  BMCBI 2006»
15 years 6 months ago
Trends in life science grid: from computing grid to knowledge grid
Background: Grid computing has great potential to become a standard cyberinfrastructure for life sciences which often require high-performance computing and large data handling wh...
Akihiko Konagaya