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BMCBI
2007
15 years 6 months ago
2007
Background: An important and yet rather neglected question related to bioinformatics predictions is the estimation of the amount of data that is needed to allow reliable predictio...
178
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BMCBI
2007
15 years 6 months ago
2007
Background: Sequence motifs representing transcription factor binding sites (TFBS) are commonly encoded as position frequency matrices (PFM) or degenerate consensus sequences (CS)...
182
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BMCBI
2007
15 years 6 months ago
2007
Background: The problem of protein structure prediction consists of predicting the functional or native structure of a protein given its linear sequence of amino acids. This probl...
158
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BMCBI
2007
15 years 6 months ago
2007
Background: RNA metabolism, through 'combinatorial splicing', can generate enormous structural diversity in the proteome. Alternative domains may interact, however, with...
163
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BMCBI
2007
15 years 6 months ago
2007
Background: There are some limitations associated with conventional clustering methods for short time-course gene expression data. The current algorithms require prior domain know...