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193
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BIOINFORMATICS
2011
15 years 1 months ago
2011
Motivation: Analysis and intervention in the dynamics of gene regulatory networks is at the heart of emerging efforts in the development of modern treatment of numerous ailments i...
209
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BIOINFORMATICS
2011
15 years 1 months ago
2011
Motivation: High-throughput methods for detecting molecular interactions have produced large sets of biological network data with much more yet to come. Analogous to sequence alig...
200
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BMCBI
2011
15 years 1 months ago
2011
Background: The accurate determination of orthology and inparalogy relationships is essential for comparative sequence analysis, functional gene annotation and evolutionary studie...
206
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BMCBI
2011
15 years 1 months ago
2011
Background: Most predictive methods currently available for the identification of protein secretion mechanisms have focused on classically secreted proteins. In fact, only two met...
200
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BMCBI
2011
15 years 1 months ago
2011
Background: Single Nucleotide Polymorphism (SNP) analysis only captures a small proportion of associated genetic variants in Genome-Wide Association Studies (GWAS) partly due to s...