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162
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BIOINFORMATICS
2004
15 years 6 months ago
2004
Motivation: A microarray experiment is a multi-step process, and each step is a potential source of variation. There are two major sources of variation: biological variation and t...
244
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BMCBI
2004
15 years 6 months ago
2004
Background: Intrinsic fluctuations due to the stochastic nature of biochemical reactions can have large effects on the response of biochemical networks. This is particularly true ...
161
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BMCBI
2004
15 years 6 months ago
2004
Background: Mass spectrometry based proteomics result in huge amounts of data that has to be processed in real time in order to efficiently feed identification algorithms and to e...
183
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BMCBI
2004
15 years 6 months ago
2004
Background: Accessible surface area (ASA) or solvent accessibility of amino acids in a protein has important implications. Knowledge of surface residues helps in locating potentia...
182
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BMCBI
2004
15 years 6 months ago
2004
Background: Hidden Markov Models (HMMs) have proven very useful in computational biology for such applications as sequence pattern matching, gene-finding, and structure prediction...