3061 search results - page 443 / 613 » interactions 2010 |
185
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BMCBI
2010
15 years 6 months ago
2010
Background: The accumulation of high-throughput data greatly promotes computational investigation of gene function in the context of complex biological systems. However, a biologi...
146
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BMCBI
2010
15 years 6 months ago
2010
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
146
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BMCBI
2010
15 years 6 months ago
2010
Background: Estimation of DNA duplex hybridization free energy is widely used for predicting cross-hybridizations in DNA computing and microarray experiments. A number of software...
181
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BMCBI
2010
15 years 6 months ago
2010
Background: Phenomenological information about regulatory interactions is frequently available and can be readily converted to Boolean models. Fully quantitative models, on the ot...
213
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BMCBI
2010
15 years 6 months ago
2010
Background: Several diseases, many of which nowadays pandemic, consist of multifactorial pathologies. Paradigmatic examples come from the immune response to pathogens, in which ca...