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BMCBI
2006
129views more  BMCBI 2006»
15 years 6 months ago
Improved alignment quality by combining evolutionary information, predicted secondary structure and self-organizing maps
Background: Protein sequence alignment is one of the basic tools in bioinformatics. Correct alignments are required for a range of tasks including the derivation of phylogenetic t...
Tomas Ohlson, Varun Aggarwal, Arne Elofsson, Rober...
BMCBI
2007
140views more  BMCBI 2007»
15 years 6 months ago
Accurate prediction of protein secondary structure and solvent accessibility by consensus combiners of sequence and structure in
Background: Structural properties of proteins such as secondary structure and solvent accessibility contribute to three-dimensional structure prediction, not only in the ab initio...
Gianluca Pollastri, Alberto J. M. Martin, Catherin...
BMCBI
2007
122views more  BMCBI 2007»
15 years 6 months ago
Dissecting complex transcriptional responses using pathway-level scores based on prior information
Background: The genomewide pattern of changes in mRNA expression measured using DNA microarrays is typically a complex superposition of the response of multiple regulatory pathway...
Harmen J. Bussemaker, Lucas D. Ward, André ...
BMCBI
2005
137views more  BMCBI 2005»
15 years 6 months ago
A configuration space of homologous proteins conserving mutual information and allowing a phylogeny inference based on pair-wise
Background: Popular methods to reconstruct molecular phylogenies are based on multiple sequence alignments, in which addition or removal of data may change the resulting tree topo...
Olivier Bastien, Philippe Ortet, Sylvaine Roy, Eri...
PR
2007
189views more  PR 2007»
15 years 6 months ago
Information cut for clustering using a gradient descent approach
We introduce a new graph cut for clustering which we call the Information Cut. It is derived using Parzen windowing to estimate an information theoretic distance measure between p...
Robert Jenssen, Deniz Erdogmus, Kenneth E. Hild II...