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BMCBI
2005
106views more  BMCBI 2005»
15 years 7 months ago
SIMPROT: Using an empirically determined indel distribution in simulations of protein evolution
Background: General protein evolution models help determine the baseline expectations for the evolution of sequences, and they have been extensively useful in sequence analysis an...
Andy Pang, Andrew D. Smith, Paulo A. S. Nuin, Elis...
BMCBI
2005
115views more  BMCBI 2005»
15 years 7 months ago
Statistical distributions of optimal global alignment scores of random protein sequences
Background: The inference of homology from statistically significant sequence similarity is a central issue in sequence alignments. So far the statistical distribution function un...
Hongxia Pang, Jiaowei Tang, Su-Shing Chen, Shiheng...
JASIS
2007
121views more  JASIS 2007»
15 years 7 months ago
Can citation analysis of Web publications better detect research fronts?
We present evidence that, in some research fields, research published in journals and reported on the Web may collectively represent different evolutionary stages of the field wit...
Dangzhi Zhao, Andreas Strotmann
BMCBI
2005
89views more  BMCBI 2005»
15 years 7 months ago
Theme discovery from gene lists for identification and viewing of multiple functional groups
Background: High throughput methods of the genome era produce vast amounts of data in the form of gene lists. These lists are large and difficult to interpret without advanced com...
Petri Pehkonen, Garry Wong, Petri Töröne...
BMCBI
2005
169views more  BMCBI 2005»
15 years 7 months ago
Genetic interaction motif finding by expectation maximization - a novel statistical model for inferring gene modules from synthe
Background: Synthetic lethality experiments identify pairs of genes with complementary function. More direct functional associations (for example greater probability of membership...
Yan Qi 0003, Ping Ye, Joel S. Bader
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