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BMCBI
2005
116views more  BMCBI 2005»
15 years 7 months ago
Can Zipf's law be adapted to normalize microarrays?
Background: Normalization is the process of removing non-biological sources of variation between array experiments. Recent investigations of data in gene expression databases for ...
Timothy Lu, Christine M. Costello, Peter J. P. Cro...
BMCBI
2005
94views more  BMCBI 2005»
15 years 7 months ago
T.I.M.S: TaqMan Information Management System, tools to organize data flow in a genotyping laboratory
Background: Single Nucleotide Polymorphism (SNP) genotyping is a major activity in biomedical research. The Taqman technology is one of the most commonly used approaches. It produ...
Stéphanie Monnier, David G. Cox, Tim Albion...
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BMCBI
2005
113views more  BMCBI 2005»
15 years 7 months ago
Alternative splicing and protein function
Background: Alternative splicing is a major mechanism of generating protein diversity in higher eukaryotes. Although at least half, and probably more, of mammalian genes are alter...
A. D. Neverov, Irena I. Artamonova, Ramil N. Nurtd...
BMCBI
2005
107views more  BMCBI 2005»
15 years 7 months ago
An edit script for taxonomic classifications
Abstract. Taxonomy provides one of the most powerful ways to navigate sequence data bases but currently, users are forced to formulate queries according to a single taxonomic class...
Roderic D. M. Page, Gabriel Valiente
BMCBI
2005
251views more  BMCBI 2005»
15 years 7 months ago
Contextual weighting for Support Vector Machines in literature mining: an application to gene versus protein name disambiguation
Background: The ability to distinguish between genes and proteins is essential for understanding biological text. Support Vector Machines (SVMs) have been proven to be very effici...
Tapio Pahikkala, Filip Ginter, Jorma Boberg, Jouni...
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