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228
Voted
BMCBI
2005
15 years 7 months ago
2005
Background: Collections of transcription factor binding profiles (Transfac, Jaspar) are essential to identify regulatory elements in DNA sequences. Subsets of highly similar profi...
250
Voted
BMCBI
2005
15 years 7 months ago
2005
Background: The alignment of multiple protein sequences is a fundamental step in the analysis of biological data. It has traditionally been applied to analyzing protein families f...
203
Voted
BMCBI
2005
15 years 7 months ago
2005
Background: The large gap between the number of protein sequences in databases and the number of functionally characterized proteins calls for the development of a fast computatio...
356
Voted
BMCBI
2005
15 years 7 months ago
2005
Background: Alignment of RNA secondary structures is important in studying functional RNA motifs. In recent years, much progress has been made in RNA motif finding and structure a...
217
Voted
BMCBI
2005
15 years 7 months ago
2005
Background: Genome wide microarray studies have the potential to unveil novel disease entities. Clinically homogeneous groups of patients can have diverse gene expression profiles...