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175
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BMCBI
2007
15 years 7 months ago
2007
Background: Transcription factors (TFs) are key regulatory proteins that enhance or repress the transcriptional rate of their target genes by binding to specific promoter regions ...
254
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BMCBI
2007
15 years 7 months ago
2007
Background: Protein remote homology detection is a central problem in computational biology. Most recent methods train support vector machines to discriminate between related and ...
209
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BMCBI
2007
15 years 7 months ago
2007
Background: This work addresses the problem of detecting conserved transcription factor binding sites and in general regulatory regions through the analysis of sequences from homo...
193
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BMCBI
2007
15 years 7 months ago
2007
Background: Efforts to predict functional sites from globular proteins is increasingly common; however, the most successful of these methods generally require structural insight. ...
196
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BMCBI
2007
15 years 7 months ago
2007
Background: Despite a remarkable success in the computational prediction of genes in Bacteria and Archaea, a lack of comprehensive understanding of prokaryotic gene structures pre...