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199
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BMCBI
2005
15 years 6 months ago
2005
Background: To standardize gene product descriptions, a formal vocabulary defined as the Gene Ontology (GO) has been developed. GO terms have been categorized into biological proc...
197
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BMCBI
2005
15 years 6 months ago
2005
Background: Exhaustive methods of sequence alignment are accurate but slow, whereas heuristic approaches run quickly, but their complexity makes them more difficult to implement. ...
180
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BMCBI
2005
15 years 6 months ago
2005
Background: We observe two trends in bioinformatics: (i) analyses are increasing in complexity, often requiring several applications to be run as a workflow; and (ii) multiple CPU...
199
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BMCBI
2005
15 years 6 months ago
2005
Background: The integration of genomic information with quantitative experimental data is a key component of systems biology. An increasing number of microbial genomes are being s...
166
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JCB
2007
15 years 6 months ago
2007
Locality is an important and well-studied notion in comparative analysis of biological sequences. Similarly, taking into account affine gap penalties when calculating biological ...