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179
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BMCBI
2005
15 years 6 months ago
2005
Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
178
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BMCBI
2005
15 years 6 months ago
2005
Background: Popular methods to reconstruct molecular phylogenies are based on multiple sequence alignments, in which addition or removal of data may change the resulting tree topo...
146
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BMCBI
2005
15 years 6 months ago
2005
Background: Despite the continuous production of genome sequence for a number of organisms, reliable, comprehensive, and cost effective gene prediction remains problematic. This i...
185
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BMCBI
2005
15 years 6 months ago
2005
Background: Many three-dimensional (3D) images are routinely collected in biomedical research and a number of digital atlases with associated anatomical and other information have...
183
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BMCBI
2005
15 years 6 months ago
2005
Background: Protein function is often dependent on subsets of solvent-exposed residues that may exist in a similar three-dimensional configuration in non homologous proteins thus ...