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BMCBI
2008
112views more  BMCBI 2008»
15 years 6 months ago
A general modeling and visualization tool for comparing different members of a group: application to studying tau-mediated regul
Background: Innumerable biological investigations require comparing collections of molecules, cells or organisms to one another with respect to one or more of their properties. Al...
Arnab Bhattacharya, Sasha Levy, Adria LeBoeuf, Mic...
BMCBI
2008
167views more  BMCBI 2008»
15 years 6 months ago
Not proper ROC curves as new tool for the analysis of differentially expressed genes in microarray experiments
Background: Most microarray experiments are carried out with the purpose of identifying genes whose expression varies in relation with specific conditions or in response to enviro...
Stefano Parodi, Vito Pistoia, Marco Muselli
BMCBI
2008
105views more  BMCBI 2008»
15 years 6 months ago
A gene pattern mining algorithm using interchangeable gene sets for prokaryotes
Background: Mining gene patterns that are common to multiple genomes is an important biological problem, which can lead us to novel biological insights. When family classification...
Meng Hu, Kwangmin Choi, Wei Su, Sun Kim, Jiong Yan...
BMCBI
2008
105views more  BMCBI 2008»
15 years 6 months ago
A Bayesian method for calculating real-time quantitative PCR calibration curves using absolute plasmid DNA standards
Background: In real-time quantitative PCR studies using absolute plasmid DNA standards, a calibration curve is developed to estimate an unknown DNA concentration. However, potenti...
Mano Sivaganesan, Shawn Seifring, Manju Varma, Ric...
BMCBI
2008
104views more  BMCBI 2008»
15 years 6 months ago
ReRep: Computational detection of repetitive sequences in genome survey sequences (GSS)
Background: Genome survey sequences (GSS) offer a preliminary global view of a genome since, unlike ESTs, they cover coding as well as non-coding DNA and include repetitive region...
Thomas D. Otto, Leonardo H. F. Gomes, Marcelo Alve...