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2011
ACM
15 years 1 months ago
Network bucket testing
Bucket testing, also known as A/B testing, is a practice that is widely used by on-line sites with large audiences: in a simple version of the methodology, one evaluates a new fea...
Lars Backstrom, Jon M. Kleinberg
NECO
2011
15 years 1 months ago
Collective Stability of Networks of Winner-Take-All Circuits
The neocortex has a remarkably uniform neuronal organization, suggesting that common principles of processing are employed throughout its extent. In particular, the patterns of co...
Ueli Rutishauser, Rodney J. Douglas, Jean-Jacques ...
BMCBI
2011
15 years 28 days ago
A theoretical entropy score as a single value to express inhibitor selectivity
Background: Designing maximally selective ligands that act on individual targets is the dominant paradigm in drug discovery. Poor selectivity can underlie toxicity and side effect...
Joost C. M. Uitdehaag, Guido J. R. Zaman
BMCBI
2011
15 years 28 days ago
Assessing the benefits of using mate-pairs to resolve repeats in de novo short-read prokaryotic assemblies
Background: Next-generation sequencing technologies allow genomes to be sequenced more quickly and less expensively than ever before. However, as sequencing technology has improve...
Joshua Wetzel, Carl Kingsford, Mihai Pop
BMCBI
2011
15 years 28 days ago
PhyloSim - Monte Carlo simulation of sequence evolution in the R statistical computing environment
Background: The Monte Carlo simulation of sequence evolution is routinely used to assess the performance of phylogenetic inference methods and sequence alignment algorithms. Progr...
Botond Sipos, Tim Massingham, Gregory E. Jordan, N...