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BMCBI
2010
124views more  BMCBI 2010»
15 years 6 months ago
A factor model to analyze heterogeneity in gene expression
Background: Microarray technology allows the simultaneous analysis of thousands of genes within a single experiment. Significance analyses of transcriptomic data ignore the gene d...
Yuna Blum, Guillaume Le Mignon, Sandrine Lagarrigu...
BMCBI
2010
134views more  BMCBI 2010»
15 years 6 months ago
R-Gada: a fast and flexible pipeline for copy number analysis in association studies
Background: Genome-wide association studies (GWAS) using Copy Number Variation (CNV) are becoming a central focus of genetic research. CNVs have successfully provided target genom...
Roger Pique-Regi, Alejandro Cáceres, Juan R...
BMCBI
2010
243views more  BMCBI 2010»
15 years 6 months ago
Comparative study of unsupervised dimension reduction techniques for the visualization of microarray gene expression data
Background: Visualization of DNA microarray data in two or three dimensional spaces is an important exploratory analysis step in order to detect quality issues or to generate new ...
Christoph Bartenhagen, Hans-Ulrich Klein, Christia...
BMCBI
2010
106views more  BMCBI 2010»
15 years 1 months ago
Identification and correction of previously unreported spatial phenomena using raw Illumina BeadArray data
Background: A key stage for all microarray analyses is the extraction of feature-intensities from an image. If this step goes wrong, then subsequent preprocessing and processing s...
Mike L. Smith, Mark J. Dunning, Simon Tavaré...
BMCBI
2010
223views more  BMCBI 2010»
15 years 1 months ago
MetNetGE: interactive views of biological networks and ontologies
Background: Linking high-throughput experimental data with biological networks is a key step for understanding complex biological systems. Currently, visualization tools for large...
Ming Jia, Suh-Yeon Choi, Dirk Reiners, Eve Syrkin ...