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BMCBI
2010
100views more  BMCBI 2010»
15 years 6 months ago
Trimming of mammalian transcriptional networks using network component analysis
Background: Network Component Analysis (NCA) has been used to deduce the activities of transcription factors (TFs) from gene expression data and the TF-gene binding relationship. ...
Linh M. Tran, Daniel R. Hyduke, James C. Liao
BMCBI
2010
135views more  BMCBI 2010»
15 years 6 months ago
Efficient genome-scale phylogenetic analysis under the duplication-loss and deep coalescence cost models
Background: Genomic data provide a wealth of new information for phylogenetic analysis. Yet making use of this data requires phylogenetic methods that can efficiently analyze extr...
Mukul S. Bansal, J. Gordon Burleigh, Oliver Eulens...
BMCBI
2010
92views more  BMCBI 2010»
15 years 6 months ago
HORI: a web server to compute Higher Order Residue Interactions in protein structures
Background: Folding of a protein into its three dimensional structure is influenced by both local and global interactions within a protein. Higher order residue interactions, like...
Pandurangan Sundaramurthy, Khader Shameer, Raashi ...
BMCBI
2010
156views more  BMCBI 2010»
15 years 6 months ago
Comparative classification of species and the study of pathway evolution based on the alignment of metabolic pathways
Background: Pathways provide topical descriptions of cellular circuitry. Comparing analogous pathways reveals intricate insights into individual functional differences among speci...
Adi Mano, Tamir Tuller, Oded Béjà, R...
BMCBI
2010
189views more  BMCBI 2010»
15 years 6 months ago
Efficient parallel and out of core algorithms for constructing large bi-directed de Bruijn graphs
Background: Assembling genomic sequences from a set of overlapping reads is one of the most fundamental problems in computational biology. Algorithms addressing the assembly probl...
Vamsi Kundeti, Sanguthevar Rajasekaran, Hieu Dinh,...