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BMCBI
2010
106views more  BMCBI 2010»
15 years 6 months ago
TumorBoost: Normalization of allele-specific tumor copy numbers from a single pair of tumor-normal genotyping microarrays
Background: High-throughput genotyping microarrays assess both total DNA copy number and allelic composition, which makes them a tool of choice for copy number studies in cancer, ...
Henrik Bengtsson, Pierre Neuvial, Terence P. Speed
BMCBI
2010
153views more  BMCBI 2010»
15 years 6 months ago
PPLook: an automated data mining tool for protein-protein interaction
Background: Extracting and visualizing of protein-protein interaction (PPI) from text literatures are a meaningful topic in protein science. It assists the identification of inter...
Shao-Wu Zhang, Yao-Jun Li, Li Xia, Quan Pan
BMCBI
2010
125views more  BMCBI 2010»
15 years 6 months ago
Large-scale prediction of protein-protein interactions from structures
Background: The prediction of protein-protein interactions is an important step toward the elucidation of protein functions and the understanding of the molecular mechanisms insid...
Martial Hue, Michael Riffle, Jean-Philippe Vert, W...
BMCBI
2010
233views more  BMCBI 2010»
15 years 6 months ago
Odefy -- From discrete to continuous models
Background: Phenomenological information about regulatory interactions is frequently available and can be readily converted to Boolean models. Fully quantitative models, on the ot...
Jan Krumsiek, Sebastian Pölsterl, Dominik M. ...
BMCBI
2010
103views more  BMCBI 2010»
15 years 6 months ago
Virtual Screening of potential drug-like inhibitors against Lysine/DAP pathway of Mycobacterium tuberculosis
Background: An explosive global spreading of multidrug resistant Mycobacterium tuberculosis (Mtb) is a catastrophe, which demands an urgent need to design or develop novel/potent ...
Aarti Garg, Rupinder Tewari, Gajendra P. S. Raghav...