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BMCBI
2010
15 years 1 months ago
2010
Background: Ribonuclease P is an ancient endonuclease that cleaves precursor tRNA and generally consists of a catalytic RNA subunit (RPR) and one or more proteins (RPPs). It repre...
168
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BMCBI
2010
15 years 6 months ago
2010
Background: Protein loops encompass 50% of protein residues in available three-dimensional structures. These regions are often involved in protein functions, e.g. binding site, ca...
174
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BMCBI
2010
15 years 6 months ago
2010
Background: A major goal of molecular biology is determining the mechanisms that control the transcription of genes. Motif Enrichment Analysis (MEA) seeks to determine which DNA-b...
165
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BMCBI
2010
15 years 6 months ago
2010
Background: DNA signatures are distinct short nucleotide sequences that provide valuable information that is used for various purposes, such as the design of Polymerase Chain Reac...
166
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BMCBI
2010
15 years 6 months ago
2010
Background: The estimation of demographic parameters from genetic data often requires the computation of likelihoods. However, the likelihood function is computationally intractab...