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BMCBI
2010
104views more  BMCBI 2010»
15 years 6 months ago
Parameters for accurate genome alignment
Background: Genome sequence alignments form the basis of much research. Genome alignment depends on various mundane but critical choices, such as how to mask repeats and which sco...
Martin C. Frith, Michiaki Hamada, Paul Horton
BMCBI
2010
175views more  BMCBI 2010»
15 years 6 months ago
Calibur: a tool for clustering large numbers of protein decoys
Background: Ab initio protein structure prediction methods generate numerous structural candidates, which are referred to as decoys. The decoy with the most number of neighbors of...
Shuai Cheng Li, Yen Kaow Ng
BMCBI
2010
105views more  BMCBI 2010»
15 years 6 months ago
GWAMA: software for genome-wide association meta-analysis
Background: Despite the recent success of genome-wide association studies in identifying novel loci contributing effects to complex human traits, such as type 2 diabetes and obesi...
Reedik Mägi, Andrew P. Morris
BMCBI
2010
175views more  BMCBI 2010»
15 years 6 months ago
Saliva Ontology: An ontology-based framework for a Salivaomics Knowledge Base
Background: The Salivaomics Knowledge Base (SKB) is designed to serve as a computational infrastructure that can permit global exploration and utilization of data and information ...
Jiye Ai, Barry Smith, Wong T. David
BMCBI
2010
150views more  BMCBI 2010»
15 years 6 months ago
Evolutionary rates at codon sites may be used to align sequences and infer protein domain function
Background: Sequence alignments form part of many investigations in molecular biology, including the determination of phylogenetic relationships, the prediction of protein structu...
Pierre M. Durand, Scott Hazelhurst, Theresa L. Coe...