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BMCBI
2010
162views more  BMCBI 2010»
15 years 3 months ago
SNPexp - A web tool for calculating and visualizing correlation between HapMap genotypes and gene expression levels
Background: Expression levels for 47294 transcripts in lymphoblastoid cell lines from all 270 HapMap phase II individuals, and genotypes (both HapMap phase II and III) of 3.96 mil...
Kristian Holm, Espen Melum, Andre Franke, Tom H. K...
BMCBI
2010
185views more  BMCBI 2010»
15 years 1 months ago
MetaPIGA v2.0: maximum likelihood large phylogeny estimation using the metapopulation genetic algorithm and other stochastic heu
Background: The development, in the last decade, of stochastic heuristics implemented in robust application softwares has made large phylogeny inference a key step in most compara...
Raphaël Helaers, Michel C. Milinkovitch
BMCBI
2010
163views more  BMCBI 2010»
15 years 1 months ago
RISCI - Repeat Induced Sequence Changes Identifier: a comprehensive, comparative genomics-based, in silico subtractive hybridiza
Background -: The availability of multiple whole genome sequences has facilitated in silico identification of fixed and polymorphic transposable elements (TE). Whereas polymorphic...
Vipin Singh, Rakesh K. Mishra
BMCBI
2010
141views more  BMCBI 2010»
15 years 6 months ago
BioPhysConnectoR: Connecting Sequence Information and Biophysical Models
Background: One of the most challenging aspects of biomolecular systems is the understanding of the coevolution in and among the molecule(s). A complete, theoretical picture of th...
Franziska Hoffgaard, Philipp Weil, Kay Hamacher
BMCBI
2010
110views more  BMCBI 2010»
15 years 6 months ago
Missing value imputation for epistatic MAPs
Background: Epistatic miniarray profiling (E-MAPs) is a high-throughput approach capable of quantifying aggravating or alleviating genetic interactions between gene pairs. The dat...
Colm Ryan, Derek Greene, Gerard Cagney, Padraig Cu...