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BMCBI
2010
155views more  BMCBI 2010»
15 years 6 months ago
A flexible R package for nonnegative matrix factorization
Background: Nonnegative Matrix Factorization (NMF) is an unsupervised learning technique that has been applied successfully in several fields, including signal processing, face re...
Renaud Gaujoux, Cathal Seoighe
BMCBI
2010
149views more  BMCBI 2010»
15 years 6 months ago
S3DB core: a framework for RDF generation and management in bioinformatics infrastructures
Background: Biomedical research is set to greatly benefit from the use of semantic web technologies in the design of computational infrastructure. However, beyond well defined res...
Jonas S. Almeida, Helena F. Deus, Wolfgang Maass
BMCBI
2010
144views more  BMCBI 2010»
15 years 6 months ago
Graph-based clustering and characterization of repetitive sequences in next-generation sequencing data
Background: The investigation of plant genome structure and evolution requires comprehensive characterization of repetitive sequences that make up the majority of higher plant nuc...
Petr Novák, Pavel Neumann, Jirí Maca...
BMCBI
2010
105views more  BMCBI 2010»
15 years 6 months ago
The Neural/Immune Gene Ontology: clipping the Gene Ontology for neurological and immunological systems
Background: The Gene Ontology (GO) is used to describe genes and gene products from many organisms. When used for functional annotation of microarray data, GO is often slimmed by ...
Nophar Geifman, Alon Monsonego, Eitan Rubin
BMCBI
2010
88views more  BMCBI 2010»
15 years 6 months ago
Robust probabilistic superposition and comparison of protein structures
Background: Protein structure comparison is a central issue in structural bioinformatics. The standard dissimilarity measure for protein structures is the root mean square deviati...
Martin Mechelke, Michael Habeck