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BMCBI
2010
107views more  BMCBI 2010»
15 years 1 months ago
Interaction prediction and classification of PDZ domains
Background: PDZ domain is a well-conserved, structural protein domain found in hundreds of signaling proteins that are otherwise unrelated. PDZ domains can bind to the C-terminal ...
Sibel Kalyoncu, Ozlem Keskin, Attila Gürsoy
BMCBI
2010
93views more  BMCBI 2010»
15 years 6 months ago
JunctionViewer: customizable annotation software for repeat-rich genomic regions
Background: Repeat-rich regions such as centromeres receive less attention than their gene-rich euchromatic counterparts because the former are difficult to assemble and analyze. ...
Thomas K. Wolfgruber, Gernot G. Presting
BMCBI
2010
166views more  BMCBI 2010»
15 years 6 months ago
Accurate peak list extraction from proteomic mass spectra for identification and profiling studies
Background: Mass spectrometry is an essential technique in proteomics both to identify the proteins of a biological sample and to compare proteomic profiles of different samples. ...
Nicola Barbarini, Paolo Magni
BMCBI
2010
120views more  BMCBI 2010»
15 years 6 months ago
Optimal contact definition for reconstruction of Contact Maps
Background: Contact maps have been extensively used as a simplified representation of protein structures. They capture most important features of a protein's fold, being pref...
Jose M. Duarte, Rajagopal Sathyapriya, Henning Ste...
BMCBI
2010
97views more  BMCBI 2010»
15 years 6 months ago
Incorporating significant amino acid pairs to identify O-linked glycosylation sites on transmembrane proteins and non-transmembr
Background: While occurring enzymatically in biological systems, O-linked glycosylation affects protein folding, localization and trafficking, protein solubility, antigenicity, bi...
Shu-An Chen, Tzong-Yi Lee, Yu-Yen Ou