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BMCBI
2006
81views more  BMCBI 2006»
15 years 6 months ago
Multipolar representation of protein structure
Background: That the structure determines the function of proteins is a central paradigm in biology. However, protein functions are more directly related to cooperative effects at...
Apostol Gramada, Philip E. Bourne
BMCBI
2006
130views more  BMCBI 2006»
15 years 6 months ago
CARMA: A platform for analyzing microarray datasets that incorporate replicate measures
Background: The incorporation of statistical models that account for experimental variability provides a necessary framework for the interpretation of microarray data. A robust ex...
Kevin A. Greer, Matthew R. McReynolds, Heddwen L. ...
BMCBI
2006
124views more  BMCBI 2006»
15 years 6 months ago
ZCURVE_V: a new self-training system for recognizing protein-coding genes in viral and phage genomes
Background: It necessary to use highly accurate and statistics-based systems for viral and phage genome annotations. The GeneMark systems for gene-finding in virus and phage genom...
Feng-Biao Guo, Chun-Ting Zhang
BMCBI
2006
145views more  BMCBI 2006»
15 years 6 months ago
Fast-Find: A novel computational approach to analyzing combinatorial motifs
Background: Many vital biological processes, including transcription and splicing, require a combination of short, degenerate sequence patterns, or motifs, adjacent to defined seq...
Micah Hamady, Erin Peden, Rob Knight, Ravinder Sin...
BMCBI
2006
95views more  BMCBI 2006»
15 years 6 months ago
A quantitative analysis of secondary RNA structure using domination based parameters on trees
Background: It has become increasingly apparent that a comprehensive database of RNA motifs is essential in order to achieve new goals in genomic and proteomic research. Secondary...
Teresa W. Haynes, Debra J. Knisley, Edith Seier, Y...