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BMCBI
2006
15 years 6 months ago
2006
Background: Microarray technology is generating huge amounts of data about the expression level of thousands of genes, or even whole genomes, across different experimental conditi...
162
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BMCBI
2006
15 years 6 months ago
2006
Background: Unigenic evolution is a powerful genetic strategy involving random mutagenesis of a single gene product to delineate functionally important domains of a protein. This ...
228
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BMCBI
2006
15 years 6 months ago
2006
Background: Various statistical and machine learning methods have been successfully applied to the classification of DNA microarray data. Simple instance-based classifiers such as...
153
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BMCBI
2006
15 years 6 months ago
2006
Background: A great deal of effort and expense are being expended internationally in attempts to detect genetic polymorphisms contributing to susceptibility to complex human disea...
165
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BMCBI
2006
15 years 6 months ago
2006
Background: Many dimeric protein complexes bind cooperatively to families of bipartite nucleic acid sequence elements, which consist of pairs of conserved half-site sequences sepa...