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162
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BMCBI
2006
15 years 6 months ago
2006
Background: Character mapping on phylogenies has played an important, if not critical role, in our understanding of molecular, morphological, and behavioral evolution. Until very ...
159
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BMCBI
2006
15 years 6 months ago
2006
Background: Simulation of DNA-microarray data serves at least three purposes: (i) optimizing the design of an intended DNA microarray experiment, (ii) comparing existing pre-proce...
172
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BMCBI
2006
15 years 6 months ago
2006
Background: Low-level processing and normalization of microarray data are most important steps in microarray analysis, which have profound impact on downstream analysis. Multiple ...
153
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BMCBI
2006
15 years 6 months ago
2006
Background: The choice of probe set algorithms for expression summary in a GeneChip study has a great impact on subsequent gene expression data analysis. Spiked-in cRNAs with know...
189
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BMCBI
2006
15 years 6 months ago
2006
Background: We present a general approach to perform association analyses in pedigrees of arbitrary size and structure, which also allows for a mixture of pedigree members and ind...