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BMCBI
2007
127views more  BMCBI 2007»
15 years 6 months ago
A Latent Variable Approach for Meta-Analysis of Gene Expression Data from Multiple Microarray Experiments
Background: With the explosion in data generated using microarray technology by different investigators working on similar experiments, it is of interest to combine results across...
Hyungwon Choi, Ronglai Shen, Arul M. Chinnaiyan, D...
BMCBI
2007
123views more  BMCBI 2007»
15 years 6 months ago
GO for gene documents
Annotating genes and their products with Gene Ontology codes is an important area of research. One approach for doing this is to use the information available about these genes in...
Padmini Srinivasan, Xin Ying Qiu
BMCBI
2007
115views more  BMCBI 2007»
15 years 6 months ago
How accurate and statistically robust are catalytic site predictions based on closeness centrality?
Background: We examine the accuracy of enzyme catalytic residue predictions from a network representation of protein structure. In this model, amino acid α-carbons specify vertic...
Eric Chea, Dennis R. Livesay
BMCBI
2007
107views more  BMCBI 2007»
15 years 6 months ago
Progressive multiple sequence alignments from triplets
Motivation: The quality of progressive sequence alignments strongly depends on the accuracy of the individual pairwise alignment steps since gaps that are introduced at one step c...
Matthias Kruspe, Peter F. Stadler
BMCBI
2007
150views more  BMCBI 2007»
15 years 6 months ago
Refining intra-protein contact prediction by graph analysis
Background: Accurate prediction of intra-protein residue contacts from sequence information will allow the prediction of protein structures. Basic predictions of such specific con...
Milana Frenkel-Morgenstern, Rachel Magid, Eran Eya...