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BMCBI
2005
80views more  BMCBI 2005»
15 years 6 months ago
Sample phenotype clusters in high-density oligonucleotide microarray data sets are revealed using Isomap, a nonlinear algorithm
Background: Life processes are determined by the organism's genetic profile and multiple environmental variables. However the interaction between these factors is inherently ...
Kevin Dawson, Raymond L. Rodriguez, Wasyl Malyj
BMCBI
2005
63views more  BMCBI 2005»
15 years 6 months ago
Individual sequences in large sets of gene sequences may be distinguished efficiently by combinations of shared sub-sequences
Background: Most current DNA diagnostic tests for identifying organisms use specific oligonucleotide probes that are complementary in sequence to, and hence only hybridise with th...
Mark J. Gibbs, John S. Armstrong, Adrian J. Gibbs
BMCBI
2005
114views more  BMCBI 2005»
15 years 6 months ago
AutoFACT: An Automatic Functional Annotation and Classification Tool
Background: Assignment of function to new molecular sequence data is an essential step in genomics projects. The usual process involves similarity searches of a given sequence aga...
Liisa B. Koski, Michael W. Gray, B. Franz Lang, Ge...
BMCBI
2005
93views more  BMCBI 2005»
15 years 6 months ago
Computing expectation values for RNA motifs using discrete convolutions
Background: Computational biologists use Expectation values (E-values) to estimate the number of solutions that can be expected by chance during a database scan. Here we focus on ...
André Lambert, Matthieu Legendre, Jean-Fred...
BMCBI
2005
150views more  BMCBI 2005»
15 years 6 months ago
Approaching the taxonomic affiliation of unidentified sequences in public databases - an example from the mycorrhizal fungi
Background: During the last few years, DNA sequence analysis has become one of the primary means of taxonomic identification of species, particularly so for species that are minut...
R. Henrik Nilsson, Erik Kristiansson, Martin Ryber...