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BMCBI
2006
124views more  BMCBI 2006»
15 years 6 months ago
Predicting transcription factor binding sites using local over-representation and comparative genomics
Background: Identifying cis-regulatory elements is crucial to understanding gene expression, which highlights the importance of the computational detection of overrepresented tran...
Matthieu Defrance, Hélène Touzet
BMCBI
2006
126views more  BMCBI 2006»
15 years 6 months ago
A minimally invasive multiple marker approach allows highly efficient detection of meningioma tumors
Background: The development of effective frameworks that permit an accurate diagnosis of tumors, especially in their early stages, remains a grand challenge in the field of bioinf...
Andreas Keller, Nicole Ludwig, Nicole Comtesse, An...
BMCBI
2006
129views more  BMCBI 2006»
15 years 6 months ago
Fast index based algorithms and software for matching position specific scoring matrices
Background: In biological sequence analysis, position specific scoring matrices (PSSMs) are widely used to represent sequence motifs in nucleotide as well as amino acid sequences....
Michael Beckstette, Robert Homann, Robert Giegeric...
BMCBI
2005
94views more  BMCBI 2005»
15 years 6 months ago
Workflows in bioinformatics: meta-analysis and prototype implementation of a workflow generator
Background: Computational methods for problem solving need to interleave information access and algorithm execution in a problem-specific workflow. The structures of these workflo...
Alexander García Castro, Samuel Thoraval, L...
BMCBI
2005
92views more  BMCBI 2005»
15 years 6 months ago
A decoy set for the thermostable subdomain from chicken villin headpiece, comparison of different free energy estimators
Background: Estimators of free energies are routinely used to judge the quality of protein structural models. As these estimators still present inaccuracies, they are frequently e...
Federico Fogolari, Silvio C. E. Tosatto, Giorgio C...