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BMCBI
2007
84views more  BMCBI 2007»
15 years 6 months ago
A comparative study of S/MAR prediction tools
Background: S/MARs are regions of the DNA that are attached to the nuclear matrix. These regions are known to affect substantially the expression of genes. The computer prediction...
Kenneth Evans, Sascha Ott, Annika Hansen, Georgy K...
BMCBI
2007
92views more  BMCBI 2007»
15 years 6 months ago
Large-scale validation of methods for cytotoxic T-lymphocyte epitope prediction
Background: Reliable predictions of Cytotoxic T lymphocyte (CTL) epitopes are essential for rational vaccine design. Most importantly, they can minimize the experimental effort ne...
Mette V. Larsen, Claus Lundegaard, Kasper Lamberth...
BMCBI
2006
164views more  BMCBI 2006»
15 years 6 months ago
BIOZON: a system for unification, management and analysis of heterogeneous biological data
Integration of heterogeneous data types is a challenging problem, especially in biology, where the number of databases and data types increase rapidly. Amongst the problems that o...
Aaron Birkland, Golan Yona
BMCBI
2006
125views more  BMCBI 2006»
15 years 6 months ago
Algebraic comparison of metabolic networks, phylogenetic inference, and metabolic innovation
Metabolic networks are naturally represented as directed hypergraphs in such a way that metabolites are nodes and enzyme-catalyzed reactions form (hyper)edges. The familiar operat...
Christian V. Forst, Christoph Flamm, Ivo L. Hofack...
BMCBI
2006
120views more  BMCBI 2006»
15 years 6 months ago
A factor analysis model for functional genomics
Background: Expression array data are used to predict biological functions of uncharacterized genes by comparing their expression profiles to those of characterized genes. While b...
Rafal Kustra, Romy Shioda, Mu Zhu