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BMCBI
2006
131views more  BMCBI 2006»
15 years 6 months ago
inGeno - an integrated genome and ortholog viewer for improved genome to genome comparisons
Background: Systematic genome comparisons are an important tool to reveal gene functions, pathogenic features, metabolic pathways and genome evolution in the era of post-genomics....
Chunguang Liang, Thomas Dandekar
BMCBI
2005
70views more  BMCBI 2005»
15 years 6 months ago
Integrating alternative splicing detection into gene prediction
Background: Alternative splicing (AS) is now considered as a major actor in transcriptome/ proteome diversity and it cannot be neglected in the annotation process of a new genome....
Sylvain Foissac, Thomas Schiex
BMCBI
2005
91views more  BMCBI 2005»
15 years 6 months ago
COPASAAR - A database for proteomic analysis of single amino acid repeats
Background: Single amino acid repeats make up a significant proportion in all of the proteomes that have currently been determined. They have been shown to be functionally and med...
Daniel P. Depledge, Andrew R. Dalby
BMCBI
2005
110views more  BMCBI 2005»
15 years 6 months ago
Considerations when using the significance analysis of microarrays (SAM) algorithm
Background: Users of microarray technology typically strive to use universally acceptable data analysis strategies to determine significant expression changes in their experiments...
Ola Larsson, Claes Wahlestedt, James A. Timmons
BMCBI
2005
88views more  BMCBI 2005»
15 years 6 months ago
Using large-scale perturbations in gene network reconstruction
Background: Recent analysis of the yeast gene network shows that most genes have few inputs, indicating that enumerative gene reconstruction methods are both useful and computatio...
Thomas MacCarthy, Andrew Pomiankowski, Robert Seym...