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BMCBI
2006
106views more  BMCBI 2006»
15 years 6 months ago
GONOME: measuring correlations between GO terms and genomic positions
Background:Current methods to find significantly under- and over-represented gene ontology (GO) terms in a set of genes consider the genes as equally probable "balls in a bag...
Stefan M. Stanley, Timothy L. Bailey, John S. Matt...
BMCBI
2005
92views more  BMCBI 2005»
15 years 6 months ago
Filtering high-throughput protein-protein interaction data using a combination of genomic features
Background: Protein-protein interaction data used in the creation or prediction of molecular networks is usually obtained from large scale or high-throughput experiments. This exp...
Ashwini Patil, Haruki Nakamura
BMCBI
2004
97views more  BMCBI 2004»
15 years 6 months ago
Calibration and assessment of channel-specific biases in microarray data with extended dynamical range
Background: Non-linearities in observed log-ratios of gene expressions, also known as intensity dependent log-ratios, can often be accounted for by global biases in the two channe...
Henrik Bengtsson, Göran Jönsson, Johan V...
BMCBI
2007
129views more  BMCBI 2007»
15 years 6 months ago
Inferring cellular networks - a review
In this review we give an overview of computational and statistical methods to reconstruct cellular networks. Although this area of research is vast and fast developing, we show t...
Florian Markowetz, Rainer Spang
BMCBI
2007
94views more  BMCBI 2007»
15 years 6 months ago
Transcriptional regulation at a glance
Considering that 80 genomes have been sequenced, providing us with the static information of the genome, it is still a long way to reveal the relationship between complex genotype...
Silke Sperling