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BMCBI
2006
85views more  BMCBI 2006»
15 years 6 months ago
On the statistical assessment of classifiers using DNA microarray data
Background: In this paper we present a method for the statistical assessment of cancer predictors which make use of gene expression profiles. The methodology is applied to a new d...
Nicola Ancona, Rosalia Maglietta, Ada Piepoli, Ann...
BMCBI
2005
92views more  BMCBI 2005»
15 years 6 months ago
A restraint molecular dynamics and simulated annealing approach for protein homology modeling utilizing mean angles
Background: We have developed the program PERMOL for semi-automated homology modeling of proteins. It is based on restrained molecular dynamics using a simulated annealing protoco...
Andreas Möglich, Daniel Weinfurtner, Till Mau...
BMCBI
2005
102views more  BMCBI 2005»
15 years 6 months ago
The Molecular Biology Toolkit (MBT): a modular platform for developing molecular visualization applications
Background: The large amount of data that are currently produced in the biological sciences can no longer be explored and visualized efficiently with traditional, specialized soft...
John L. Moreland, Apostol Gramada, Oleksandr V. Bu...
BMCBI
2005
144views more  BMCBI 2005»
15 years 6 months ago
GeneRank: Using search engine technology for the analysis of microarray experiments
Background: Interpretation of simple microarray experiments is usually based on the fold-change of gene expression between a reference and a "treated" sample where the t...
Julie L. Morrison, Rainer Breitling, Desmond J. Hi...
BMCBI
2005
96views more  BMCBI 2005»
15 years 6 months ago
Comparison of codon usage measures and their applicability in prediction of microbial gene expressivity
Background: There are a number of methods (also called: measures) currently in use that quantify codon usage in genes. These measures are often influenced by other sequence proper...
Fran Supek, Kristian Vlahovicek