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BMCBI
2006
90views more  BMCBI 2006»
15 years 6 months ago
Dissecting trait heterogeneity: a comparison of three clustering methods applied to genotypic data
Background: Trait heterogeneity, which exists when a trait has been defined with insufficient specificity such that it is actually two or more distinct traits, has been implicated...
Tricia A. Thornton-Wells, Jason H. Moore, Jonathan...
BMCBI
2006
95views more  BMCBI 2006»
15 years 6 months ago
A simple method for assessing sample sizes in microarray experiments
In this short article, we discuss a simple method for assessing sample size requirements in microarray experiments. Our method starts with the output from a permutation-based anal...
Robert Tibshirani
BMCBI
2006
64views more  BMCBI 2006»
15 years 6 months ago
In silico modelling of hormone response elements
Background: An important step in understanding the conditions that specify gene expression is the recognition of gene regulatory elements. Due to high diversity of different types...
Maria Stepanova, Feng Lin, Valerie C.-L. Lin
BMCBI
2006
105views more  BMCBI 2006»
15 years 6 months ago
Prediction of protein submitochondria locations by hybridizing pseudo-amino acid composition with various physicochemical featur
Background: Knowing the submitochondria localization of a mitochondria protein is an important step to understand its function. We develop a method which is based on an extended v...
Pufeng Du, Yanda Li
BMCBI
2006
100views more  BMCBI 2006»
15 years 6 months ago
Chromosomal patterns of gene expression from microarray data: methodology, validation and clinical relevance in gliomas
Background: Expression microarrays represent a powerful technique for the simultaneous investigation of thousands of genes. The evidence that genes are not randomly distributed in...
Federico E. Turkheimer, Federico Roncaroli, Benoit...