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BMCBI
2007
148views more  BMCBI 2007»
15 years 6 months ago
fREDUCE: Detection of degenerate regulatory elements using correlation with expression
Background: The precision of transcriptional regulation is made possible by the specificity of physical interactions between transcription factors and their cognate binding sites ...
Randy Z. Wu, Christina Chaivorapol, Jiashun Zheng,...
BMCBI
2007
113views more  BMCBI 2007»
15 years 6 months ago
Analysis and prediction of antibacterial peptides
Background: Antibacterial peptides are important components of the innate immune system, used by the host to protect itself from different types of pathogenic bacteria. Over the l...
Sneh Lata, B. K. Sharma, G. P. S. Raghava
BMCBI
2007
159views more  BMCBI 2007»
15 years 6 months ago
Computational genes: a tool for molecular diagnosis and therapy of aberrant mutational phenotype
Background: A finite state machine manipulating information-carrying DNA strands can be used to perform autonomous molecular-scale computations at the cellular level. Results: We ...
Israel Mark Martínez-Pérez, Gong Zha...
BMCBI
2007
144views more  BMCBI 2007»
15 years 6 months ago
Motif kernel generated by genetic programming improves remote homology and fold detection
Background: Protein remote homology detection is a central problem in computational biology. Most recent methods train support vector machines to discriminate between related and ...
Tony Håndstad, Arne J. H. Hestnes, Pål...
BMCBI
2007
86views more  BMCBI 2007»
15 years 6 months ago
Tandem mass spectrometry data quality assessment by self-convolution
Background: Many algorithms have been developed for deciphering the tandem mass spectrometry (MS) data sets. They can be essentially clustered into two classes. The first performs...
Keng Wah Choo, Wai Mun Tham