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BMCBI
2007
115views more  BMCBI 2007»
15 years 6 months ago
Correlation between structure and temperature in prokaryotic metabolic networks
Background: In recent years, an extensive characterization of network structures has been made in an effort to elucidate design principles of metabolic networks, providing valuabl...
Kazuhiro Takemoto, Jose C. Nacher, Tatsuya Akutsu
BMCBI
2007
142views more  BMCBI 2007»
15 years 6 months ago
Support Vector Machine-based method for predicting subcellular localization of mycobacterial proteins using evolutionary informa
Background: In past number of methods have been developed for predicting subcellular location of eukaryotic, prokaryotic (Gram-negative and Gram-positive bacteria) and human prote...
Mamoon Rashid, Sudipto Saha, Gajendra P. S. Raghav...
BMCBI
2007
216views more  BMCBI 2007»
15 years 6 months ago
A replica exchange Monte Carlo algorithm for protein folding in the HP model
Background: The ab initio protein folding problem consists of predicting protein tertiary structure from a given amino acid sequence by minimizing an energy function; it is one of...
Chris Thachuk, Alena Shmygelska, Holger H. Hoos
BMCBI
2007
102views more  BMCBI 2007»
15 years 6 months ago
qPIPSA: Relating enzymatic kinetic parameters and interaction fields
Background: The simulation of metabolic networks in quantitative systems biology requires the assignment of enzymatic kinetic parameters. Experimentally determined values are ofte...
Razif R. Gabdoulline, Matthias Stein, Rebecca C. W...
BMCBI
2007
106views more  BMCBI 2007»
15 years 6 months ago
Discovering functional linkages and uncharacterized cellular pathways using phylogenetic profile comparisons: a comprehensive as
Background: A widely-used approach for discovering functional and physical interactions among proteins involves phylogenetic profile comparisons (PPCs). Here, proteins with simila...
Raja Jothi, Teresa M. Przytycka, L. Aravind