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BMCBI
2007
147views more  BMCBI 2007»
15 years 6 months ago
MaxAlign: maximizing usable data in an alignment
Background: The presence of gaps in an alignment of nucleotide or protein sequences is often an inconvenience for bioinformatical studies. In phylogenetic and other analyses, for ...
Rodrigo Gouveia-Oliveira, Peter Wad Sackett, Ander...
BMCBI
2007
133views more  BMCBI 2007»
15 years 6 months ago
Semantic integration to identify overlapping functional modules in protein interaction networks
Background: The systematic analysis of protein-protein interactions can enable a better understanding of cellular organization, processes and functions. Functional modules can be ...
Young-Rae Cho, Woochang Hwang, Murali Ramanathan, ...
BMCBI
2007
112views more  BMCBI 2007»
15 years 6 months ago
Integrated olfactory receptor and microarray gene expression databases
Background: Gene expression patterns of olfactory receptors (ORs) are an important component of the signal encoding mechanism in the olfactory system since they determine the inte...
Nian Liu, Chiquito J. Crasto, Minghong Ma
BMCBI
2007
139views more  BMCBI 2007»
15 years 6 months ago
Improving model predictions for RNA interference activities that use support vector machine regression by combining and filterin
Background: RNA interference (RNAi) is a naturally occurring phenomenon that results in the suppression of a target RNA sequence utilizing a variety of possible methods and pathwa...
Andrew S. Peek
BMCBI
2007
227views more  BMCBI 2007»
15 years 6 months ago
Growing functional modules from a seed protein via integration of protein interaction and gene expression data
Background: Nowadays modern biology aims at unravelling the strands of complex biological structures such as the protein-protein interaction (PPI) networks. A key concept in the o...
Ioannis A. Maraziotis, Konstantina Dimitrakopoulou...