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BMCBI
2004
96views more  BMCBI 2004»
15 years 6 months ago
Gene finding in novel genomes
Background: Computational gene prediction continues to be an important problem, especially for genomes with little experimental data. Results: I introduce the SNAP gene finder whi...
Ian Korf
BMCBI
2004
124views more  BMCBI 2004»
15 years 6 months ago
Tests for finding complex patterns of differential expression in cancers: towards individualized medicine
Background: Microarray studies in cancer compare expression levels between two or more sample groups on thousands of genes. Data analysis follows a population-level approach (e.g....
James Lyons-Weiler, Satish Patel, Michael J. Becic...
BMCBI
2004
177views more  BMCBI 2004»
15 years 6 months ago
Gapped alignment of protein sequence motifs through Monte Carlo optimization of a hidden Markov model
Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...
Andrew F. Neuwald, Jun S. Liu
BMCBI
2004
115views more  BMCBI 2004»
15 years 6 months ago
An SVD-based comparison of nine whole eukaryotic genomes supports a coelomate rather than ecdysozoan lineage
Background: Eukaryotic whole genome sequences are accumulating at an impressive rate. Effective methods for comparing multiple whole eukaryotic genomes on a large scale are needed...
Gary W. Stuart, Michael W. Berry
BMCBI
2004
87views more  BMCBI 2004»
15 years 6 months ago
Selection of informative clusters from hierarchical cluster tree with gene classes
Background: A common clustering method in the analysis of gene expression data has been hierarchical clustering. Usually the analysis involves selection of clusters by cutting the...
Petri Törönen