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BMCBI
2006
15 years 6 months ago
2006
Background: Availability of high-resolution RNA crystal structures for the 30S and 50S ribosomal subunits and the subsequent validation of comparative secondary structure models h...
179
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BMCBI
2006
15 years 6 months ago
2006
Background: Microarrays permit biologists to simultaneously measure the mRNA abundance of thousands of genes. An important issue facing investigators planning microarray experimen...
173
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BMCBI
2006
15 years 6 months ago
2006
Background: Differentially expressed genes are typically identified by analyzing the variation between replicate measurements. These procedures implicitly assume that there are no...
153
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BMCBI
2006
15 years 6 months ago
2006
Background: Both direct and indirect interactions determine molecular recognition of ligands by proteins. Indirect interactions can be defined as effects on recognition controlled...
149
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BMCBI
2006
15 years 6 months ago
2006
Background: Does a relationship exist between a protein's evolutionary rate and its number of interactions? This relationship has been put forward many times, based on a biol...