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BMCBI
2006
75views more  BMCBI 2006»
15 years 6 months ago
A machine learning strategy to identify candidate binding sites in human protein-coding sequence
Background: The splicing of RNA transcripts is thought to be partly promoted and regulated by sequences embedded within exons. Known sequences include binding sites for SR protein...
Thomas Down, Bernard Leong, Tim J. P. Hubbard
BMCBI
2005
153views more  BMCBI 2005»
15 years 6 months ago
A comparative review of estimates of the proportion unchanged genes and the false discovery rate
Background: In the analysis of microarray data one generally produces a vector of p-values that for each gene give the likelihood of obtaining equally strong evidence of change by...
Per Broberg
BMCBI
2005
93views more  BMCBI 2005»
15 years 6 months ago
SPdb - a signal peptide database
Background: The signal peptide plays an important role in protein targeting and protein translocation in both prokaryotic and eukaryotic cells. This transient, short peptide seque...
Khar Heng Choo, Tin Wee Tan, Shoba Ranganathan
BMCBI
2005
104views more  BMCBI 2005»
15 years 6 months ago
Scoring functions for transcription factor binding site prediction
Background: Transcription factor binding site (TFBS) prediction is a difficult problem, which requires a good scoring function to discriminate between real binding sites and backg...
Markus T. Friberg, Peter von Rohr, Gaston H. Gonne...
BMCBI
2005
89views more  BMCBI 2005»
15 years 6 months ago
Comparative analysis of chromatin landscape in regulatory regions of human housekeeping and tissue specific genes
Background: Global regulatory mechanisms involving chromatin assembly and remodelling in the promoter regions of genes is implicated in eukaryotic transcription control especially...
Mythily Ganapathi, Pragya Srivastava, Sushanta Kum...