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BMCBI
2006
15 years 6 months ago
2006
Background: The main processing pathway for MHC class I ligands involves degradation of proteins by the proteasome, followed by transport of products by the transporter associated...
156
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BMCBI
2006
15 years 6 months ago
2006
Background: Various experimental techniques yield peptides that are biologically active but have unfavourable pharmacological properties. The design of structurally similar organi...
170
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BMCBI
2006
15 years 6 months ago
2006
Background: Genetic markers hold great promise for refining our ability to establish precise prognostic prediction for diseases. The development of comprehensive gene expression m...
180
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BMCBI
2006
15 years 6 months ago
2006
Background: Defensins are antimicrobial peptides of innate immunity functioning by non-specific binding to anionic phospholipids in bacterial membranes. Their cationicity, amphipa...
183
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BMCBI
2006
15 years 6 months ago
2006
Background: Modelling the interaction between potentially antigenic peptides and Major Histocompatibility Complex (MHC) molecules is a key step in identifying potential T-cell epi...