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BMCBI
2004
97views more  BMCBI 2004»
15 years 6 months ago
Performance of a genetic algorithm for mass spectrometry proteomics
Background: Recently, mass spectrometry data have been mined using a genetic algorithm to produce discriminatory models that distinguish healthy individuals from those with cancer...
Neal O. Jeffries
BMCBI
2004
139views more  BMCBI 2004»
15 years 6 months ago
mlstdbNet - distributed multi-locus sequence typing (MLST) databases
Background: Multi-locus sequence typing (MLST) is a method of typing that facilitates the discrimination of microbial isolates by comparing the sequences of housekeeping gene frag...
Keith A. Jolley, Man-Suen Chan, Martin C. J. Maide...
BMCBI
2004
125views more  BMCBI 2004»
15 years 6 months ago
A functional hierarchical organization of the protein sequence space
Background: It is a major challenge of computational biology to provide a comprehensive functional classification of all known proteins. Most existing methods seek recurrent patte...
Noam Kaplan, Moriah Friedlich, Menachem Fromer, Mi...
BMCBI
2004
131views more  BMCBI 2004»
15 years 6 months ago
A web services choreography scenario for interoperating bioinformatics applications
Background: Very often genome-wide data analysis requires the interoperation of multiple databases and analytic tools. A large number of genome databases and bioinformatics applic...
Remko de Knikker, Youjun Guo, Jin-long Li, Albert ...
BMCBI
2004
161views more  BMCBI 2004»
15 years 6 months ago
Three-parameter lognormal distribution ubiquitously found in cDNA microarray data and its application to parametric data treatme
Background: To cancel experimental variations, microarray data must be normalized prior to analysis. Where an appropriate model for statistical data distribution is available, a p...
Tomokazu Konishi