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BMCBI
2005
153views more  BMCBI 2005»
15 years 6 months ago
Mining published lists of cancer related microarray experiments: Identification of a gene expression signature having a critical
Background: Routine application of gene expression microarray technology is rapidly producing large amounts of data that necessitate new approaches of analysis. The analysis of a ...
Giacomo Finocchiaro, Francesco Mancuso, Heiko M&uu...
BMCBI
2005
125views more  BMCBI 2005»
15 years 6 months ago
Query3d: a new method for high-throughput analysis of functional residues in protein structures
Background: The identification of local similarities between two protein structures can provide clues of a common function. Many different methods exist for searching for similar ...
Gabriele Ausiello, Allegra Via, Manuela Helmer-Cit...
BMCBI
2005
160views more  BMCBI 2005»
15 years 6 months ago
Data-poor categorization and passage retrieval for Gene Ontology Annotation in Swiss-Prot
Background: In the context of the BioCreative competition, where training data were very sparse, we investigated two complementary tasks: 1) given a Swiss-Prot triplet, containing...
Frédéric Ehrler, Antoine Geissbü...
BMCBI
2005
132views more  BMCBI 2005»
15 years 6 months ago
CLPM: A Cross-Linked Peptide Mapping Algorithm for Mass Spectrometric Analysis
Background: Protein-protein, protein-DNA and protein-RNA interactions are of central importance in biological systems. Quadrapole Time-of-flight (Q-TOF) mass spectrometry is a sen...
Yong Tang, Yingfeng Chen, Cheryl F. Lichti, Roger ...
BMCBI
2005
125views more  BMCBI 2005»
15 years 6 months ago
A simple approach for protein name identification: prospects and limits
Background: Significant parts of biological knowledge are available only as unstructured text in articles of biomedical journals. By automatically identifying gene and gene produc...
Katrin Fundel, Daniel Güttler, Ralf Zimmer, J...