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BMCBI
2005
110views more  BMCBI 2005»
15 years 6 months ago
ProGenExpress: Visualization of quantitative data on prokaryotic genomes
Background: The integration of genomic information with quantitative experimental data is a key component of systems biology. An increasing number of microbial genomes are being s...
Michael Watson
BMCBI
2005
156views more  BMCBI 2005»
15 years 6 months ago
A new dynamical layout algorithm for complex biochemical reaction networks
Background: To study complex biochemical reaction networks in living cells researchers more and more rely on databases and computational methods. In order to facilitate computatio...
Katja Wegner, Ursula Kummer
BMCBI
2005
114views more  BMCBI 2005»
15 years 6 months ago
Extension of Lander-Waterman theory for sequencing filtered DNA libraries
Background: The degree to which conventional DNA sequencing techniques will be successful for highly repetitive genomes is unclear. Investigators are therefore considering various...
Michael C. Wendl, W. Bradley Barbazuk
BMCBI
2005
152views more  BMCBI 2005»
15 years 6 months ago
Improved profile HMM performance by assessment of critical algorithmic features in SAM and HMMER
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
Markus Wistrand, Erik L. L. Sonnhammer
BMCBI
2005
113views more  BMCBI 2005»
15 years 6 months ago
Systematic survey reveals general applicability of "guilt-by-association" within gene coexpression networks
Background: Biological processes are carried out by coordinated modules of interacting molecules. As clustering methods demonstrate that genes with similar expression display incr...
Cecily J. Wolfe, Isaac S. Kohane, Atul J. Butte