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BMCBI
2005
94views more  BMCBI 2005»
15 years 6 months ago
A method for finding single-nucleotide polymorphisms with allele frequencies in sequences of deep coverage
Background: The allele frequencies of single-nucleotide polymorphisms (SNPs) are needed to select an optimal subset of common SNPs for use in association studies. Sequence-based m...
Jianmin Wang, Xiaoqiu Huang
BMCBI
2005
135views more  BMCBI 2005»
15 years 6 months ago
A robust two-way semi-linear model for normalization of cDNA microarray data
Background: Normalization is a basic step in microarray data analysis. A proper normalization procedure ensures that the intensity ratios provide meaningful measures of relative e...
Deli Wang, Jian Huang, Hehuang Xie, Liliana Manzel...
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BMCBI
2005
105views more  BMCBI 2005»
15 years 6 months ago
SNPHunter: a bioinformatic software for single nucleotide polymorphism data acquisition and management
Background: Single nucleotide polymorphisms (SNPs) provide an important tool in pinpointing susceptibility genes for complex diseases and in unveiling human molecular evolution. S...
Lin Wang, Simin Liu, Tianhua Niu, Xin Xu
BMCBI
2005
107views more  BMCBI 2005»
15 years 6 months ago
Protein subcellular localization prediction for Gram-negative bacteria using amino acid subalphabets and a combination of multip
Background: Predicting the subcellular localization of proteins is important for determining the function of proteins. Previous works focused on predicting protein localization in...
Jiren Wang, Wing-Kin Sung, Arun Krishnan, Kuo-Bin ...
BMCBI
2005
167views more  BMCBI 2005»
15 years 6 months ago
Cross-platform analysis of cancer microarray data improves gene expression based classification of phenotypes
Background: The extensive use of DNA microarray technology in the characterization of the cell transcriptome is leading to an ever increasing amount of microarray data from cancer...
Patrick Warnat, Roland Eils, Benedikt Brors