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BMCBI
2005
127views more  BMCBI 2005»
15 years 6 months ago
Are scale-free networks robust to measurement errors?
Background: Many complex random networks have been found to be scale-free. Existing literature on scale-free networks has rarely considered potential false positive and false nega...
Nan Lin, Hongyu Zhao
BMCBI
2005
103views more  BMCBI 2005»
15 years 6 months ago
Quadratic regression analysis for gene discovery and pattern recognition for non-cyclic short time-course microarray experiments
Background: Cluster analyses are used to analyze microarray time-course data for gene discovery and pattern recognition. However, in general, these methods do not take advantage o...
Hua Liu, Sergey Tarima, Aaron S. Borders, Thomas V...
BMCBI
2005
201views more  BMCBI 2005»
15 years 6 months ago
Principal component analysis for predicting transcription-factor binding motifs from array-derived data
Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
Yunlong Liu, Matthew P. Vincenti, Hiroki Yokota
BMCBI
2005
151views more  BMCBI 2005»
15 years 6 months ago
stam - a Bioconductor compliant R package for structured analysis of microarray data
Background: Genome wide microarray studies have the potential to unveil novel disease entities. Clinically homogeneous groups of patients can have diverse gene expression profiles...
Claudio Lottaz, Rainer Spang
BMCBI
2005
116views more  BMCBI 2005»
15 years 6 months ago
Can Zipf's law be adapted to normalize microarrays?
Background: Normalization is the process of removing non-biological sources of variation between array experiments. Recent investigations of data in gene expression databases for ...
Timothy Lu, Christine M. Costello, Peter J. P. Cro...