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BMCBI
2005
15 years 6 months ago
2005
Background: Human heart failure is a complex disease that manifests from multiple genetic and environmental factors. Although ischemic and non-ischemic heart disease present clini...
148
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BMCBI
2005
15 years 6 months ago
2005
Background: Recent studies have shown that the patterns of linkage disequilibrium observed in human populations have a block-like structure, and a small subset of SNPs (called tag...
196
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BMCBI
2005
15 years 6 months ago
2005
Background: Multiple genome alignment is an important problem in bioinformatics. An important subproblem used by many multiple alignment approaches is that of aligning two multipl...
183
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BMCBI
2005
15 years 6 months ago
2005
Background: Protein sequence motifs are by definition short fragments of conserved amino acids, often associated with a specific function. Accordingly protein sequence profiles de...
200
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BMCBI
2005
15 years 6 months ago
2005
Background: The evaluation of statistical significance has become a critical process in identifying differentially expressed genes in microarray studies. Classical p-value adjustm...