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BMCBI
2005
253views more  BMCBI 2005»
15 years 6 months ago
The Use of Edge-Betweenness Clustering to Investigate Biological Function in Protein Interaction Networks
Background: This paper describes an automated method for finding clusters of interconnected proteins in protein interaction networks and retrieving protein annotations associated ...
Ruth Dunn, Frank Dudbridge, Christopher M. Sanders...
BMCBI
2005
302views more  BMCBI 2005»
15 years 6 months ago
CGHPRO - A comprehensive data analysis tool for array CGH
Background: Array CGH (Comparative Genomic Hybridisation) is a molecular cytogenetic technique for the genome wide detection of chromosomal imbalances. It is based on the cohybrid...
Wei Chen, Fikret Erdogan, H.-Hilger Ropers, Steffe...
BMCBI
2005
133views more  BMCBI 2005»
15 years 6 months ago
Systematic determination of the mosaic structure of bacterial genomes: species backbone versus strain-specific loops
Background: Public databases now contain multitude of complete bacterial genomes, including several genomes of the same species. The available data offers new opportunities to add...
Hélène Chiapello, I. Bourgait, F. So...
BMCBI
2005
80views more  BMCBI 2005»
15 years 6 months ago
Gene finding in the chicken genome
Background: Despite the continuous production of genome sequence for a number of organisms, reliable, comprehensive, and cost effective gene prediction remains problematic. This i...
Eduardo Eyras, Alexandre Reymond, Robert Castelo, ...
BMCBI
2005
150views more  BMCBI 2005»
15 years 6 months ago
Discover protein sequence signatures from protein-protein interaction data
Background: The development of high-throughput technologies such as yeast two-hybrid systems and mass spectrometry technologies has made it possible to generate large protein-prot...
Jianwen Fang, Ryan J. Haasl, Yinghua Dong, Gerald ...